Concepedia

Bioactive Streptoglutarimides A–J from the Marine-Derived <i>Streptomyces</i> sp. ZZ741

Di Zhang, Wenwen Yi, Hengju Ge, Zhizhen Zhang, Bin Wu

Journal of Natural Products · 2019 · 54 citations · 36 references

Concepts

PharmacyBiochemistryMedicinal ChemistryDrug DiscoveryMass Spectrometric AnalysisStructure-activity RelationshipsMarine Drug DiscoveryNatural Product Drug DiscoveryStructure-activity Relationship AnalysisAntimicrobial Marine CompoundsAntiproliferative AgentsAntiproliferative Drug ActionBioactive Marine MetabolitesLead Compound IdentificationMarine Actinomycetes As Drug SourcesSingle-crystal DiffractionSingle-crystal X-ray Diffraction

Abstract

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References

36

Optimization of parameters for semiempirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters

James J. P. Stewart · Journal of Molecular Modeling · 2012 · 2K citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +15

Beyond DP4: an Improved Probability for the Stereochemical Assignment of Isomeric Compounds using Quantum Chemical Calculations of NMR Shifts

Nicolás Grimblat, Marı́a M. Zanardi, Ariel M. Sarotti · The Journal of Organic Chemistry · 2015 · 1.3K citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +8

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Tilman Schneider‐Poetsch, Jianhua Ju, Daniel E. Eyler et al. · Nature Chemical Biology · 2010 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Confab - Systematic generation of diverse low-energy conformers

Noel M. O’Boyle, Tim Vandermeersch, Christopher J. Flynn et al. · Journal of Cheminformatics · 2011 · 326 citations · Full text

Life Sciences, Bioinformatics, Computational Chemistry +15

Migrastatin analogues target fascin to block tumour metastasis

Lin Chen, Shengyu Yang, Jean Jakoncic et al. · Nature · 2010 · 264 citations · Full text

Medicine, Oncology, Pharmacology +12