Concepedia

Identification of a Nine-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival of Pancreatic Cancer

Mengwei Wu, Xiaobin Li, Taiping Zhang, Ziwen Liu, Yupei Zhao

Frontiers in Oncology · 2019 · 243 citations · 45 references

DOIFull text

Open access

Concepts

Abstract

Our study identified a nine-gene signature and established a prognostic nomogram that reliably predict overall survival in pancreatic cancer. The findings may be beneficial to therapeutic customization and medical decision-making.

References

45

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang, Brad T. Sherman, Richard A. Lempicki · Nature Protocols · 2008 · 37.4K citations

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Tissue-based map of the human proteome

Mathias Uhlén, Linn Fagerberg, Björn M. Hallström et al. · Science · 2015 · 15.9K citations · Full text

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Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

Jianjiong Gao, Bülent Arman Aksoy, Uğur Doğrusöz et al. · Science Signaling · 2013 · 15.9K citations · Full text

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STRING v10: protein–protein interaction networks, integrated over the tree of life

Damian Szklarczyk, Andrea Franceschini, Stefan Wyder et al. · Nucleic Acids Research · 2014 · 11.1K citations · Full text

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