Multistep Solvent-Free 3 m² Footprint Pilot Miniplant for the Synthesis of Annual Half-Ton Rufinamide Precursor

Abstract

giving a productivity of 47 g/h (>400 kg/year), which increases by a factor of 7 the lab-scale productivity previously reported as a scale-up proof-of-concept. This publication also includes an economic study of the feasible implementation of this technology for a possible manufacturer, as well as an outline on business development strategies of how to implement such a disruptive technology.