Spinal cord stimulation prevents paclitaxel-induced mechanical and cold hypersensitivity and modulates spinal gene expression in rats

Eellan Sivanesan, Kimberly Stephens, Qian Huang, Zhiyong Chen, Neil C. Ford, Wanru Duan, Shao-Qui He, Xinyan Gao, Bengt Linderoth, Srinivasa N. Raja,

PAIN Reports · 2019 · 33 citations · 50 references

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Abstract

Our findings suggest that traditional SCS may attenuate the development of pain-related behaviors in PIPN rats, possibly by causing aggregate inhibition of synaptic plasticity through upregulation and downregulation of gene networks in the spinal cord.

References

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