The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance - Concepedia

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The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance

DOI Full Paper Access

302

Citations

35

References

2019

Year

So‐Yeon Park, Choong-Jae Lee, Jang-Hyun Choi, Jee‐Heun Kim, Ji‐Won Kim, Ji Young Kim, Jeong‐Seok Nam

Journal of Experimental & Clinical Cancer Research

Abstract

Herein, we first identified JAK2/STAT3/CCND2 signaling as a resistance mechanism for the persistent growth of CSCs after RT, suggesting potential biomarkers and regimens for improving outcomes among CRC patients.

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