Network toxicology and LC-MS-based metabolomics: New approaches for mechanism of action of toxic components in traditional Chinese medicines

Multiscale Modeling of Inflammation-Induced Tumorigenesis Reveals Competing Oncogenic and Oncoprotective Roles for Inflammation

Yucheng Guo, Qing Nie, Adam L. MacLean et al. · Cancer Research · 2017 · 124 citations · Full text

Triptolide disrupts fatty acids and peroxisome proliferator-activated receptor (PPAR) levels in male mice testes followed by testicular injury: A GC–MS based metabolomics study

Bo Ma, Huanhuan Qi, Jing Li et al. · Toxicology · 2015 · 110 citations

Male Mice Testes, Metabolic Syndrome, Andrology +9

Metabolomics and its application to the evaluation of the efficacy and toxicity of traditional Chinese herb medicines

Jian Shi, Bei Cao, Xinwen Wang et al. · Journal of Chromatography B · 2015 · 84 citations

Biochemistry, Medicine, Herbal Medicine +7

Network Pharmacology Bridges Traditional Application and Modern Development of Traditional Chinese Medicine

Changxiao Liu, Rui Liu, Huirong Fan et al. · Chinese Herbal Medicines · 2015 · 62 citations

Traditional Medicine, Pharmacological Study, Traditional Chinese Medicine +7

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Ke Lan, Mingming Su, Guoxiang Xie et al. · Analytical Chemistry · 2016 · 58 citations · Full text

Key Role, Engineering, Metabolomic Profiling +18