Tranexamic acid or epsilon-aminocaproic acid in total joint arthroplasty? A randomized controlled trial

Abstract

For hip and knee arthroplasty procedures, EACA is associated with increased perioperative blood loss compared with TXA. However, there is no significant difference in transfusion rate. While further prospective studies are needed to compare the efficacy of each agent, we currently recommend orthopaedic surgeons to select their antifibrinolytic based on cost and regional availability. Cite this article: <i>Bone Joint J</i> 2019;101-B:1093-1099.