Concepedia

Characterization of Ultraviolet Photoreactions in Therapeutic Peptides by Femtosecond Laser Catalysis and Mass Spectrometry

Simon K. Gammelgaard, Steffen B. Petersen, Kim F. Haselmann, Peter Kresten Nielsen

ACS Omega · 2019 · 10 citations · 38 references

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Concepts

Abstract

loss, and disruption of an unstable disulfide bond into a complex mixture of a trisulfide bond and multiple scrambled dimeric products. In conclusion, femtosecond lasers are extremely useful to drive fast UV-induced reactions for high throughput screening of photostability and modifications in amino acid polymers.

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