JAMA Oncology · 2019 · 127 citations · 3 references
ImmunodeficienciesImmunologyImmunotherapeuticsImmunotherapySurveillance DataImmune DysregulationTumor ImmunityRadiation OncologyMolecular OncologyCancer ResearchTumor Mutational BurdenAutoimmune DiseaseMedicineImmune SurveillanceAutoimmunityDatabase StudyImmune-related Adverse EventsInborn Error Of ImmunityAnti–pd-1 TherapyCancer ImmunosurveillanceCancer EpidemiologyImmune Checkpoint InhibitorOncology
This database study compares surveillance data on immune-related adverse events (irAEs) in patients treated with immune checkpoint inhibitors to determine whether irAEs experienced during anti–PD-1 therapy correlate with tumor mutational burden across 18 cancer types.
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