Jan Diekmann

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Uğur Şahin, Evelyna Derhovanessian, Matthias Miller et al. · Nature · 2017 · 2.4K citations

Vaccination, Allergy, Medicine +11

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Lena M. Kranz, Mustafa Diken, Heinrich Haas et al. · Nature · 2016 · 1.7K citations

Cancer Immunosurveillance, Systemic Rna Delivery, Immunology +8

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

Sebastian Kreiter, Mathias Vormehr, Niels van de Roemer et al. · Nature · 2015 · 1.2K citations · Full text

Immune Evasion, Cancer Immunosurveillance, Immunology +10

Exploiting the Mutanome for Tumor Vaccination

John C. Castle, Sebastian Kreiter, Jan Diekmann et al. · Cancer Research · 2012 · 812 citations · Full text

Immunology, Immunotherapeutics, Immunotherapy +19

A vaccine targeting mutant IDH1 induces antitumour immunity

Theresa Schumacher, Lukas Bunse, Stefan Pusch et al. · Nature · 2014 · 685 citations

Immunology, Tumor Immunity, Immunoediting +2