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Publication | Open Access

Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation

DOIFull Paper Access

14

Citations

45

References

2019

Year

K. Scott Baker, Anna K. Kopec, Asmita Pant, Lauren G. Poole, Holly Cline-Fedewa, Dora Ivkovich, Mojtaba Olyaee, Benjamin L. Woolbright, Adam Miszta, Hartmut Jaeschke,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

The results indicate that bile acids directly accelerate TF:FVIIa-driven coagulation reactions, suggesting a novel mechanism whereby elevation in a physiological mediator can directly increase TF:FVIIa procoagulant activity.

References

YearCitations

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