Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

Life Sciences, Genetics, Molecular Genetics +17

Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

Karen D. McCullough, Jennifer L. Martindale, Lars‐Oliver Klotz et al. · Molecular and Cellular Biology · 2001 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response

Jonathan H. Lin, Han Li, Douglas Yasumura et al. · Science · 2007 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

Sara B. Cullinan, Donna Zhang, Mark Hannink et al. · Molecular and Cellular Biology · 2003 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

Thaddeus P. Dryja, Terri L. McGee, Elias Reichel et al. · Nature · 1990 · 1.1K citations

Medicine, Genetics, Molecular Genetics +12