Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +17

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

Maximiliano G. Gutiérrez, Sharon Master, Sudha Singh et al. · Cell · 2004 · 2.2K citations · Full text

Life Sciences, Immunology, Microbiology +16

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Nao Hosokawa, Taichi Hara, Takeshi Kaizuka et al. · Molecular Biology of the Cell · 2009 · 2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

Julia Joung, Silvana Konermann, Jonathan S. Gootenberg et al. · Nature Protocols · 2017 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +14