Nicholas C. O. Tomkinson

The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution

Stacey A. Jones, Linda B. Moore, Jennifer L. Shenk et al. · Molecular Endocrinology · 2000 · 557 citations · Full text

Human Pxr, Genetics, Reproductive Biology +20

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Natalie H. Theodoulou, Paul Bamborough, Andrew J. Bannister et al. · Journal of Medicinal Chemistry · 2015 · 229 citations · Full text

Chemical Biology, Chromatin, Molecular Characterization +14

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

Marie Pariollaud, Julie Gibbs, Thomas Hopwood et al. · Journal of Clinical Investigation · 2018 · 195 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +19

A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis

Cinta Diez-Ardanuy, Jennifer Greaves, Kevin R. Munro et al. · Scientific Reports · 2017 · 192 citations · Full text

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry

Jennifer Greaves, Kevin R. Munro, Stuart C. Davidson et al. · Proceedings of the National Academy of Sciences · 2017 · 156 citations · Full text