Scanning ultrasound in the absence of blood-brain barrier opening is not sufficient to clear β-amyloid plaques in the APP23 mouse model of Alzheimer's disease

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

Jeff Sevigny, Ping Chiao, Thierry Bussière et al. · Nature · 2016 · 3K citations

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +7

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +11

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

Christine Stürchler-Pierrat, Dorothée Abramowski, Mairead Duke et al. · Proceedings of the National Academy of Sciences · 1997 · 1.5K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Transgenic Mouse Models +15

Transcranial Pulsed Ultrasound Stimulates Intact Brain Circuits

Yusuf Tufail, Alexei Matyushov, N.G. Baldwin et al. · Neuron · 2010 · 963 citations · Full text

Stimulation Device, Focused Ultrasound, Neurophysiology +10

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

Nir Lipsman, Ying Meng, Allison Bethune et al. · Nature Communications · 2018 · 897 citations · Full text