Concepedia

Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis

Marcus Koppitz, Nico Bräuer, Antonius ter Laak, Horst Irlbacher, Andrea Rotgeri, Anne-Marie Coelho, Daryl S. Walter, Andreas Steinmeyer, Thomas M. Zollner, Michaele Peters,

Bioorganic & Medicinal Chemistry Letters · 2019 · 11 citations · 9 references

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9

Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.6K citations

Best of Both Worlds: Combining Pharma Data and State of the Art Modeling Technology To Improve <i>in Silico</i> p<i>K</i><sub>a</sub> Prediction

Robert Fraczkiewicz, Mario Lobell, Andreas H. Göller et al. · Journal of Chemical Information and Modeling · 2014 · 103 citations · Full text

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Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats

Pascal Tétreault, Marc‐André Dansereau, Louis Doré-Savard et al. · Physiology & Behavior · 2011 · 95 citations

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Molecular and preclinical basis to inhibit PGE <sub>2</sub> receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis

Joe A. Arosh, JeHoon Lee, Dakshnapriya Balasubbramanian et al. · Proceedings of the National Academy of Sciences · 2015 · 84 citations · Full text

Endometriosis-induced vaginal hyperalgesia in the rat: Effect of estropause, ovariectomy, and estradiol replacement

Karen J. Berkley, Stacy L. McAllister, Briane E. Accius et al. · Pain · 2007 · 81 citations · Full text

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