Organic Letters · 2019 · 41 citations · 83 references
A transition-metal-free and environmentally friendly synthesis method for bromobenzothiazines through tandem C-H amination/bromination was reported. This reaction contains both intramolecular C-H amination and site-selective electrophilic bromination of arenes with NaBr as the bromo source, PhI(OAc)<sub>2</sub> or K<sub>2</sub>S<sub>2</sub>O<sub>8</sub> as the oxidant, and H<sub>2</sub>O as the only solvent.
83
Total synthesis of eudesmane terpenes by site-selective C–H oxidations
Ke Chen, Phil S. Baran · Nature · 2009 · 418 citations