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Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability

Medicinal ChemistryBiochemistryPyridine RingNatural SciencesMedicineAntimalarial ActivityAntiparasitic AgentCaco-2 Cell-based PermeabilityPharmacologyPharmaceutical ChemistryDrug DiscoveryDrug Resistance