<p>Efficacy of combinations of colistin with other antimicrobials involves membrane fluidity and efflux machinery</p>

Abstract

The alterations in the cellular efflux machinery that resulted in higher intracellular concentrations of acridine orange, and likely of other antimicrobials combined with data of membrane fluidity and measured synergism in vitro allow us to envisage the use of these combinations to fight infections caused by multidrug-resistant bacteria.