Investigation of PPIX-Lipo-MnO2 to enhance photodynamic therapy by improving tumor hypoxia

The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in Radiotherapy

L. H. Gray, Alan D. Conger, M. Ebert et al. · British Journal of Radiology · 1953 · 2.2K citations

Medicine, Cancer Biology, Oncology +14

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

Michael Höckel, Karlheinz Schlenger, Bernard Aral et al. · PubMed · 1996 · 1.7K citations

Medicine, Gynecology, Oncology +13

Intelligent Albumin–MnO₂ Nanoparticles as pH‐/H₂O₂‐Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy

Qian Chen, Liangzhu Feng, Jingjing Liu et al. · Advanced Materials · 2016 · 1K citations

Pharmacy, Oncology, Pharmaceutics +17

Cobalt Inhibits the Interaction between Hypoxia-inducible Factor-α and von Hippel-Lindau Protein by Direct Binding to Hypoxia-inducible Factor-α

Yong Yuan, George M. Hilliard, Tsuneo Ferguson et al. · Journal of Biological Chemistry · 2003 · 636 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Multifunctional Albumin–MnO₂ Nanoparticles Modulate Solid Tumor Microenvironment by Attenuating Hypoxia, Acidosis, Vascular Endothelial Growth Factor and Enhance Radiation Response

Preethy Prasad, Cláudia R. Gordijo, Azhar Z. Abbasi et al. · ACS Nano · 2014 · 626 citations

Medicine, Bioengineering, Oncology +17