Concepedia

An experimental study on polymorph control and continuous heterogeneous crystallization of carbamazepine

Chuntian Hu, Christopher J. Testa, Brianna T. Shores, Wei Wu, Khrystyna Shvedova, Stephen C. Born, Saptarshi Chattopadhyay, Bayan Takizawa, Salvatore Mascia

CrystEngComm · 2019 · 25 citations · 52 references

DOI

Concepts

Abstract

Influences of superstaturation, stirring, anti-solvent, and polymer type on polymorph are investigated.

References

52

End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

Salvatore Mascia, Patrick L. Heider, Haitao Zhang et al. · Angewandte Chemie International Edition · 2013 · 600 citations · Full text

, , +15

Comparison of the Four Anhydrous Polymorphs of Carbamazepine and the Crystal Structure of Form I**Supplementary material: X‐ray crystallographic information file (CIF) of triclinic CBZ (form I) is available.

Adam L. Grzesiak, Meidong Lang, Ki‐Bum Kim et al. · Journal of Pharmaceutical Sciences · 2003 · 509 citations · Full text

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Theory of particulate processes-analysis and techniques of continuous crystallization

Gary W. Poehlein, L. A. Wenzel · Journal of Colloid and Interface Science · 1972 · 495 citations

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Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

Spencer D. Schaber, Dimitrios I. Gerogiorgis, Rohit Ramachnadran et al. · Industrial & Engineering Chemistry Research · 2011 · 477 citations · Full text

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Continuous Processing in the Pharmaceutical Industry

K. Plumb · Process Safety and Environmental Protection · 2005 · 436 citations

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