Towards proton arc therapy: physical and biologically equivalent doses with increasing number of beams in pediatric brain irradiation

Laura Toussaint, Daniel J. Indelicato, Katrine S. Holgersen, Jørgen B. B. Petersen, Camilla H. Stokkevåg, Yasmin Lassen–Ramshad, Oscar Casares-Magaz, Anne Vestergaard, L.P. Muren

Acta Oncologica · 2019 · 42 citations · 11 references

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Concepts

Abstract

Proton arc therapy has the potential to improve dose gradients to better spare cognitive brain structures. However, this is at the expense of increased low-dose/low-LET volumes, with possible implications for secondary cancer risks.

References

11