Journal of the Royal Society of Medicine · 1990 · 40 citations · 10 references
MedicineEndocrinologyOrthopaedic SurgeryOrthopedicsWomen's HealthWomen's Health PharmacotherapyBone HealthHormonal ManagementMenopause CareMenopause Hormone TherapyMenopause ManagementOsteoporosisClinical ContraindicationsOsteoporosis In WomenPostmenopausal Osteoporosis Treatment
In Nottingham we have assessed the acceptability of oral hormone replacement therapy (HRT) for an at risk group of post-menopausal women for osteoporosis. One hundred post-menopausal women between the ages of 50 and 70 years who had sustained a distal radial fracture were offered oral HRT. There was a 36% overall uptake of HRT with 9% of patients unable to take HRT because they had medical contraindications. The uptake in the 50-55 year age group was 54%. We conclude that in prospective studies of HRT for osteoporosis up to 50% of patients may not wish to take HRT and therefore study design should allow for this level of uptake.
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LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN
R. Lindsay, J. M. Aitken, L.B. Anderson et al. · The Lancet · 1976 · 956 citations