Facile synthesis of α-trifluoromethylthio phosphonium ylides with a constrained trifluoromethylthiooxide <i>via</i> a proton-transfer procedure

Abstract

Synthesis of α-trifluoromethylthio(CF3S-)phosphonium ylides is easily accomplished with a constrained trifluoromethylthiooxide via a proton-transfer procedure without extra base. These CF3S-substituted phosphonium ylides could be applied to Wittig reactions to provide functionalised alkenes in one-pot with high yields.