Journal of Pediatric Gastroenterology and Nutrition · 2005 · 699 citations · 69 references
Ulcerative colitis and Crohn disease can manifest before age 20 in 25–30 % of all inflammatory bowel disease cases, yet reported incidence rates vary widely, underscoring the need for multicenter, multinational collaboration. The study aims to establish uniform diagnostic work‑up and criteria for pediatric inflammatory bowel disease. Diagnosis relies on a comprehensive program that includes colonoscopy with ileal intubation, upper gastrointestinal endoscopy, radiologic contrast imaging of the small bowel (unless ulcerative colitis is definite), and multiple biopsies from all gastrointestinal segments. The Porto diagnostic criteria, developed by consensus of the ESPGHAN IBD working group, provide the needed tool for uniform diagnosis.
ABSTRACT Ulcerative colitis and Crohn disease may present before the age of 20 years in 25% to 30% of all patients with inflammatory bowel disease. Reported incidence figures vary considerably depending on the collection of data. Multicenter, multinational collaboration is needed when studying pediatric inflammatory bowel disease. The essential first step is uniformity in the work‐up and criteria used for diagnosis. The Porto diagnostic criteria presented here provide the tool that is needed. These criteria are the result of consensus reached by the ESPGHAN inflammatory bowel disease working group. Diagnosis of Crohn disease, ulcerative colitis and indeterminate colitis is based on clinical signs and symptoms, endoscopy and histology and radiology. Every child suspected of inflammatory bowel disease should undergo a complete diagnostic program consisting of colonoscopy with ileal intubation, upper gastrointestinal endoscopy and (in all cases except in definite ulcerative colitis) radiologic contrast imaging of the small bowel. Multiple biopsies from all segments of the gastrointestinal tract are needed for a complete histologic evaluation. A diagnosis of indeterminate colitis cannot be made unless a full diagnostic program has been performed.
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Christoph Gasché, Jürgen Schölmerich, Geert D’Haens et al. · Inflammatory Bowel Diseases · 2000 · 1.1K citations · Full text
Vienna 1998, Functional Gastrointestinal Disorder, Simple Classification +13
Subra Kugathasan, Robert H. Judd, Raymond G. Hoffmann et al. · The Journal of Pediatrics · 2003 · 608 citations
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