Concepedia

Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro

Toshio Fujino, Yoshihisa Kobayashi, Kenichi Suda, T. Koga, Masaya Nishino, Shuta Ohara, Masato Chiba, Masaki Shimoji, Kenji Tomizawa, Toshiki Takemoto,

Journal of Thoracic Oncology · 2019 · 175 citations · 38 references

Open access

Concepts

MedicineOncologyPharmacologyCancer GeneticsMolecular OncologyNeoplasiaChemotherapy ResistanceLung CancerLung Cancer PharmacotherapyTyrosine Kinase InhibitorsKinase Inhibitor ResistanceKinase Mutation-mediated ResistanceMet InhibitorsMet Receptor Tyrosine KinaseProtein Kinase InhibitorsResistance To Tyrosine Kinase InhibitorsTyrosine Kinase Inhibitor Therapy

References

38

Comprehensive molecular profiling of lung adenocarcinoma

Nature · 2014 · 5.8K citations · Full text

Medicine, Genetics, Oncology +17

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

Lecia V. Sequist, Belinda A. Waltman, Dora Dias‐Santagata et al. · Science Translational Medicine · 2011 · 3.6K citations · Full text

Medicine, Genetics, Oncology +17

Somatic mutations affect key pathways in lung adenocarcinoma

Li Ding, Gad Getz, David A. Wheeler et al. · Nature · 2008 · 2.7K citations · Full text

Medicine, Genetics, Oncology +16

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

Marcin Imieliński, Alice H. Berger, Peter S. Hammerman et al. · Cell · 2012 · 1.8K citations · Full text

Medicine, Molecular Biology, Oncology +14

Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers

Ryohei Katayama, Alice T. Shaw, Tahsin Khan et al. · Science Translational Medicine · 2012 · 1.3K citations

Medicine, Oncology, Pharmacology +17