Thrombodynamics: a new method to the diagnosis of hemostasis system disorders

Abstract

Blood clotting disorders are one of the leading direct causes of death in developed countries. Laboratory tests are used to detect abnormalities in the hemostasis system and to monitor drug therapy. Standard tests of hemostasis have a number of limitations, so until now, there is a search and development of new, more informative and sensitive methods. One such device is thrombodynamics, a new method for studying hemostasis by measuring the growth rate of a fibrin clot. This review presents the algorithms for performing the thrombodynamics test and the interpretation of the state of the clotting system in blood plasma using this method, as well as a critical analysis of the existing base of clinical studies of thrombodynamics.