Phosphorylation of derivatives of β‐dialkyaminocrotonitriles with phosphorus(III) halides

Abstract

Abstract The reaction of β‐dialkylaminocrotontriles with phosphorus(III) halides has been investigated. The basicity of the dialkylamino group influences the phosphorylation markedly, with pyrrolidine being the amine of choice. It was found that a solvent and the ratio of triethylamine play a significant role in phosphorylation. Although chloro‐ and dichlorophosphine derivatives proved impossible to separate as individual compounds; their solutions can be successfully used for further transformations. © 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:194–201, 2009; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20532