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The Oxa-Pictet-Spengler Reaction of 1-(3-Furyl)alkan-2-ols
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2002
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Cross-coupling ReactionEngineeringAlkene MetathesisOrganic ChemistryOrganometallic CatalysisCatalysisMolecular CatalysisOxa-pictet-spengler ReactionChemistryHeterocycle ChemistrySynthetic ChemistryBiomolecular EngineeringGood YieldsP-toluenesulfonic Acid
The oxa-Pictet-Spengler reaction of 1-(3-furyl)alkan-2-ols with aldehydes catalyzed by p-toluenesulfonic acid gives good yields of the corresponding cis-5,7-disubstituted 4,5-dihydro-7H-furano[2,3-c]pyrans.