Concepedia

A New and Efficient Method for the Isomerization of Secondary Functional Allylic Alcohols into their Primary Isomers

Imen Beltaïef, Souhaïra Hbaïeb, Rafâa Besbes, Hassen Amri, Monique Villiéras, J. Villiéras

Synthesis · 1998 · 16 citations · 0 references

DOI

Concepts

Abstract

Baylis-Hillman reaction - (E/Z)-2-cyano-2-(hydroxymethyl)alk-2-enes - ethyl (E)-2-(hydroxymethyl)alk-2-enoates - isomerization - tandem bromination-formylation-hydrolysis