Tin-Free Radical Sequences under Acidic Conditions. Convergent Access to Azole-Containing Structures

Abstract

[reaction: see text] Various xanthates add efficiently to olefins bearing [1,2,4]triazole, imidazole, or benzimidazole moieties in the presence of camphorsulfonic acid via a radical chain reaction initiated by a small amount of lauroyl peroxide. The adducts may be transformed to more complex molecules by implementing a further radical cyclization.