Stereoselective synthesis of vinylogous peptides

Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination.

W. Clark Still, Cesare Gennari · Tetrahedron Letters · 1983 · 1K citations

Natural Sciences, Chemistry, Organic Chemistry +2

Peptidomimetics—Tailored Enzyme Inhibitors

Joachim Gante · Angewandte Chemie International Edition in English · 1994 · 817 citations

Pharmacy, Biochemistry, Medicinal Chemistry +11

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

Henry I. Mosberg, R. P. Hurst, Victor J. Hruby et al. · Proceedings of the National Academy of Sciences · 1983 · 739 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates

JEAN M. HAMBROOK, Barry A. Morgan, Michael J. Rance et al. · Nature · 1976 · 517 citations

Life Sciences, Neurobiology, Neuroscience +5

Design of peptides, proteins, and peptidomimetics in chi space

Victor J. Hruby, Guigen Li, Carrie Haskell‐Luevano et al. · Biopolymers · 1997 · 354 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17