Highly <i>syn</i>-Diastereoselective Synthesis of <i>NH</i>-3-Benzyloxy-4-aryl-azetidin-2-ones via a Two-Step Staudinger Reaction - Concepedia

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Highly <i>syn</i>-Diastereoselective Synthesis of <i>NH</i>-3-Benzyloxy-4-aryl-azetidin-2-ones via a Two-Step Staudinger Reaction

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1998

Year

Sergio Bacchi, Alessandro Bongini, Mauro Panunzio, Marzia Villa

Asymmetric CatalysisEnantioselective SynthesisEngineeringTwo-step Staudinger ReactionOrganic ChemistryNew ConditionsStereoselective SynthesisChemistryComplete Cis-diastereoselectivitySynthetic ChemistryStaudinger ReactionBiomolecular Engineering

Abstract

New conditions for the Staudinger reaction provide NH-3-benzyloxy-4-aryl-β-lactams in good yields with complete cis-diastereoselectivity.