Synthesis of Glufosinate via Amidocarbonylation

Shinichiro Takigawa, Shuzo Shinke, Masato Tanaka

Chemistry Letters · 1990 · 12 citations · 9 references

Concepts

Abstract

Abstract Cobalt carbonyl-catalyzed carbonylation of methylvinylphosphinate with acetamide followed by hydrolysis gave 2-amino-4-[hydroxy(methyl)phosphinyl]butanoic acid (glufosinate) in more than 80% overall yield.

References

9