Concepedia

Synthesis of Griseolic Acid B by π-Face-Dependent Radical Cyclization

Spencer Knapp, Machender R. Madduru, Zhijian Lu, Gregori J. Morriello, Thomas J. Emge, George A. Doss

Organic Letters · 2001 · 12 citations · 5 references

DOI

Concepts

Abstract

[reaction: see text]. Radical cyclization of 6 affords the bicyclic vinyl ether 9 with the appropriate stereochemistry for elaboration (seven steps) to griseolic acid B (1).

References

5

Structure assignments in polysubstituted ethylenes by nuclear magnetic resonance

Stephen W. Tobey · The Journal of Organic Chemistry · 1969 · 89 citations

, , +7

Total synthesis of griseolic acid derivatives from D-glucose

Deen Bhandu Tulshian, Ronald J. Doll, Mary F. Stansberry et al. · The Journal of Organic Chemistry · 1991 · 30 citations

, , +6

Biological properties of griseolic acid, a cyclic AMP phosphodiesterase inhibitor with an adenine group

Yasuteru Iijima, Fumio Nakagawa, Shuji Handa et al. · FEBS Letters · 1985 · 13 citations

, , +16

Photolyses of trienes. III. Photoreactions of 2,3,7,7-tetramethyl-cycloheptatriene

L. B. Jones, Vera K. Jones · The Journal of Organic Chemistry · 1969 · 12 citations

, , +6

Total Synthesis of Griseolic Acid

Deen Tulshian, Michael Czarniecki · Journal of the American Chemical Society · 1995 · 12 citations

, , +6