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Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL–quinine–squaramide: efficient access to optically active nitro-alkanes and their isoxazole derivatives

1,3-Dicarbonyl CompoundsEngineeringNatural SciencesDiversity-oriented SynthesisOrganic ChemistryIsoxazole DerivativesCatalysisChemistryDesigner Chiral Binol–quinine–squaramideAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering