Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia

Yue Huang, Rui Su, Yue Sheng, +25

Cancer Cell

Hematological MalignancyBiochemistryNatural SciencesAcute Myeloid LeukemiaMixed-phenotype Acute Leukemia +6

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance

Yi Liu, Guanghao Liang, Hongjiao Xu, +17

Cell Metabolism

Tumor BiologyCancer ImmunosurveillanceMalignant DiseaseMedicineImmunology +12

Chemical Inhibitors Targeting the Oncogenic m⁶A Modifying Proteins

Yue Huang, Wenyang Xia, Ze Dong, +1

Accounts of Chemical Research

A Pair of Windmill-Shaped Enantiomers from <i>Lindera aggregata</i> with Activity toward Improvement of Insulin Sensitivity

Fei Wang, Yuan Gao, Ling Zhang, +6

Organic Letters

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

Tiziano Bernasocchi, Geniver El Tekle, Marco Bolis, +29

Nature Communications

Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties

Pan Xiao, Zongliang Duan, Zeyu Liu, +7

Journal of Medicinal Chemistry

Chiral squaramide as multiple H-bond donor organocatalysts for the asymmetric Michael addition of 1,3-dicarbonyl compounds to nitroolefins

Ze Dong, Guofu Qiu, Hai‐Bing Zhou, +1

Tetrahedron Asymmetry

Novel Organocatalysts1,3-Dicarbonyl CompoundsEngineeringOrganic ChemistryChiral Squaramide +5

Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL–quinine–squaramide: efficient access to optically active nitro-alkanes and their isoxazole derivatives

Bin Liu, Xin Han, Ze Dong, +3

Tetrahedron Asymmetry

1,3-Dicarbonyl CompoundsEngineeringNatural SciencesDiversity-oriented SynthesisOrganic Chemistry +8

Structure–Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors

Zeyu Liu, Zongliang Duan, Deyan Zhang, +9

Journal of Medicinal Chemistry

Tunable Bifunctional Phosphine–Squaramide Promoted Morita–Baylis–Hillman Reaction of <i>N</i>‐Alkyl Isatins with Acrylates

Ze Dong, Chao Guo Yan, Yongzhi Gao, +3

Advanced Synthesis & Catalysis

Inorganic ChemistryCross-coupling ReactionNovel OrganocatalystsP NmrEngineering +12