Reactivity of 1‐(2‐nitrophenyl)‐5‐aminopyrazoles under basic conditions and synthesis of new 3‐, 7‐, and 8‐substituted pyrazolo[5,1‐<i>c</i>][1,2,4]benzotriazine 5‐oxides, as benzodiazepine receptor ligands

Abstract

Abstract The reaction of 1‐(2‐nitrophenyl)‐5‐aminopyrazoles under basic conditions has been reinvestigated and the structures of the obtained pyrazolo[5,1‐ c ][1,2,4]benzotriazine 5‐oxides confirmed by spectroscopic means. In particular the different aromatic nucleophilic attack on 8‐chloro derivatives 4a and 6a and 7‐nitro derivatives 11a and 12a was determined. From these latter compounds unexpected (phenyl‐ ONN ‐azoxy)pyrazoles were isolated.