Three‐Component One‐Pot Synthesis of α‐Hydroxylamino Phosphonates using Ionic Liquids

Abstract

Abstract α‐Hydroxylamino phosphonates are synthesised in a one‐pot operation by three‐component coupling reactions of aldehydes, hydroxylamines and diethyl phosphite using 1‐butyl‐3‐methylimidazolium tetrafluoroborate ([bmim]BF 4 ) or 1‐butyl‐3‐methylimidazolium hexafluorophosphate ([bmim]PF 6 ) ionic liquids under mild and neutral conditions. The recovered ionic liquids can be recycled for four to five runs without loss of activity.