Synlett · 2003 · 16 citations · 0 references
Natural SciencesChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryMacrocycle SynthesisOrganic SynthesisPericyclic ReactionsRetrosynthetic AnalysisClaisen RearrangementPericyclic Reaction MechanismsPericyclic ReactivityPericyclic Rearrangement StrategiesPericyclic StereochemistryWittig Reaction
The account summarizes the development of the ester dienolate [2,3]-Wittig rearrangement as a versatile synthetic tool for the construction of highly substituted 3-alkoxycarbonyl-3-hydroxy-substituted 1,5-hexadienes. Furthermore, the account provides an insight into a novel sequential pericyclic reaction employing the 1,5-hexadienes accessible through the ester dienolate [2,3]-Wittig rearrangement.