Direct Preparation of Saccharin Skeletons from <i>N</i>-Methyl(<i>o</i>-methyl)arenesulfonamides with (Diacetoxyiodo)arenes

Abstract

Various N-methylsaccharins were easily prepared in moderate to good yields by the reaction of N-methyl(o-methyl)arenesulfonamides with (diacetoxyiodo)arene in the presence of iodine under irradiation with a tungsten lamp. The present method is very useful for the direct preparation of saccharins with N-methyl(o-methyl)arenesulfonamides containing various substituents on the aromatic ring.