Concepedia

Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity

Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu,

Theranostics · 2019 · 201 citations · 36 references

DOIFull text

Open access

Concepts

Abstract

signaling could be a new mechanism of mitochondrial transplantation to rescue aerobic respiration and attenuate the Warburg effect. This mechanism could be a promising approach for radiosensitization.

References

36

THE METABOLISM OF TUMORS IN THE BODY

Otto Warbürg, Franz Wind, Erwin Negelein · The Journal of General Physiology · 1927 · 4.4K citations · Full text

, , +17

On the origin of mitosing cells

Journal of Theoretical Biology · 1967 · 1.7K citations

, , +12

Transfer of mitochondria from astrocytes to neurons after stroke

Kazuhide Hayakawa, Elga Esposito, Xiaohua Wang et al. · Nature · 2016 · 1.4K citations · Full text

, , +10

Mitochondrial transfer between cells can rescue aerobic respiration

Jeffrey L. Spees, Scott D. Olson, Mandolin J. Whitney et al. · Proceedings of the National Academy of Sciences · 2006 · 1.1K citations · Full text

, , +13

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

Anne-Marie B. Brillantes, Karol Ondriaš, Andrew Scott et al. · Cell · 1994 · 817 citations

, , +16