A synthetic receptor for dinucleotides

Amalia Galán, Javier de Mendoza, Catherine Toiron, Marta Bruix, Ghislain Deslongchamps, Julius Rebek

Journal of the American Chemical Society · 1991 · 71 citations · 0 references

Abstract

Complexation of biorelevant targets with synthetic receptors continues to provide information regarding recognition at the molecular level.2 One tactic involves the concatenation of modular subunits with complementarity to specific domains of the target. Here we apply this means to develop a system (receptor 1) for the complexation of 2'-deoxyadenylyl(3,->5')-2,-deoxyadenosine (<f(AA)) and give evidence of its success.