Synthesis and properties of 4,5‐dihydrobenzo[<i>e</i>]imidazo[2,1‐<i>c</i>][1,4,2]diazaphosphinine derivatives

Abstract

Abstract A number of 4,5‐dihydrobenzo[ e ]imidazo[2,1‐ c ][1,4,2]diazaphosphinine derivatives were prepared by the direct phosphorylation of 1‐(4‐Chlorophenylcarboxamido)‐2‐(1H‐1‐imidazolyl)‐5‐trifluoromethylbenzene in basic medium with phosphorus(III) bromide and dibromophenylphosphine. The tricyclic compounds 6a, 6b , and 9 having a trivalent phosphorus atom undergo the diazaphosphinine ring opening upon treatment with secondary amines in the presence of sulfur. © 2002 John Wiley &amp; Sons, Inc. Heteroatom Chem 13:84–92, 2002; DOI 10.1002/hc.10000