A New Entry to Oxacycles via Base-Catalyzed Endo Mode Cyclization of Allenyl Sulfoxides and Sulfones

Abstract

[reaction: see text]. Treatment of the allenyl sulfoxides and sulfones possessing a proper delta-hydroxy appendage at the C-1 position with potassium tert-butoxide effected endo mode ring closure at the sp-hybridized carbon center of the allenyl moiety to provide the five- to eight-membered oxacycles in high yields.