Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico

Carlos Francisco Madrazo-Moya, Irving Cancino‐Muñoz, Betzaida Cuevas-Córdoba, Vanessa González-Covarrubias, Martín Barbosa-Amezcua, Xavier Soberón, Raquel Muñiz‐Salazar, Armando Martínez-Guarneros, Claudia E. Bäcker, José Zarrabal-Meza,

PLoS ONE · 2019 · 30 citations · 44 references

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Abstract

The results illustrate the utility of WGS for establishing the potential for prediction of resistance against first and second line drugs in isolates of tuberculosis from the region. They also demonstrate the feasibility of this procedure for use as a tool to support the epidemiological surveillance of drug- and multidrug-resistant tuberculosis.

References

44