Synthesis of β-hydroxy nitriles and 1,3-amino alcohols from epoxides using acetone cyanohydrin as a LiCN precursor

Chemoenzymatic synthesis2 of both enantiomers of fluoxetine, tomoxetine and nisoxetine: lipase-catalyzed resolution of 3-aryl-3-hydroxypropanenitriles

Ähmed Kamal, Garima Khanna, R. Ramu · Tetrahedron Asymmetry · 2002 · 109 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Micellar media for the efficient ring opening of epoxides with CN–, N3–, NO3–, NO2–, SCN–, Cl– and Br– catalyzed with Ce(OTf)4

Nasser Iranpoor, Habib Firouzabadi, Marzieh Shekarize · Organic & Biomolecular Chemistry · 2003 · 74 citations

Natural Sciences, Chemistry, Catalysis +8

Efficient Lipase-Catalyzed Kinetic Resolution and Dynamic Kinetic Resolution of β-Hydroxy Nitriles. A Route to Useful Precursors for γ-Amino Alcohols

Òscar Pàmies, Jan‐E. Bäckvall · Advanced Synthesis & Catalysis · 2001 · 73 citations

Life Sciences, Biochemistry, Biotechnology +17

Enantioselective Total Syntheses of the 5,11-Methanomorphanthridine <i>Amaryllidaceae</i> Alkaloids (−)-Pancracine and (−)-Coccinine

Jian Jin, Steven M. Weinreb · Journal of the American Chemical Society · 1997 · 73 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Easy direct stereo- and regioselective formation of β-hydroxy nitriles by reaction of 1,2-epoxides with potassium cyanide in the presence of metal salts

Marco Chini, Paolo Crotti, Lucilla Favero et al. · Tetrahedron Letters · 1991 · 71 citations

Natural Sciences, Chemistry, Catalysis +6