Concepedia

Tandem Decarboxylative Allylation and Fragmentation of Allyl Benzocyclobutenyl Carbonates: Access to ortho-Functionalized Aryls from Aryl Bromides

Arturo Orellana, David Rosa, Andrei Chtchemelinine

Synthesis · 2012 · 14 citations · 0 references

Concepts

Natural SciencesChemistryCatalysisOrganic ChemistryCatalytic MechanismsCross-coupling ReactionsOrganic SynthesisRetrosynthetic AnalysisAllylic FunctionalizationAsymmetric Cross-couplingC - C Coupling CatalysisC-c Coupling CatalysisCross CouplingDecarboxylative CouplingDecarboxylative Cross-couplingPalladium-catalyzed Cross-coupling

Abstract

Allyl benzocyclobutyl carbonates yield ortho-allyl α-aryl ketones through a palladium-catalyzed decarboxylative allylation, fragmentation, and cross-coupling process.