Aaptanone, a novel zwitterionic metabolite of the aaptamine class with an oxygenated 1,6-naphthyridine core from the Vietnamese marine sponge Aaptos aaptos

Isolation and structure of aaptamine a novel heteroaromatic substance possessing α-blocking activity from the sea sponge

Hideshi Nakamura, Jun’ichi Kobayashi, Yasushi Ohizumi et al. · Tetrahedron Letters · 1982 · 125 citations

Medicine, Marine Biology, Pharmacology +16

Evaluation of Marine Sponge Metabolites for Cytotoxicity and Signal Transduction Activity

Ross E. Longley, Oliver J. McConnell, Eberhard Essich et al. · Journal of Natural Products · 1993 · 107 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Novel alkaloids of the aaptamine class from an Indonesian marine sponge of the genus Xestospongia

Laurent Calcul, Arlette Longeon, Ali Al‐Mourabit et al. · Tetrahedron · 2003 · 92 citations

Natural Sciences, Marine Biology, Marine Sciences +12

Coscinamides A, B and C, three new bis indole alkaloids from the marine sponge Coscinoderma sp.

Heidi R. Bokesch, Lewis K. Pannell, Tawnya C. McKee et al. · Tetrahedron Letters · 2000 · 76 citations

Natural Sciences, Marine Biology, Marine Sciences +11

Modification at the C9 position of the marine natural product isoaaptamine and the impact on HIV-1, mycobacterial, and tumor cell activity

Waseem Gul, Nicholas L. Hammond, Muhammad Yousaf et al. · Bioorganic & Medicinal Chemistry · 2006 · 65 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +11