Concepedia

α-Hydroxy Cyclopentenones from α-Diketones

William A. Batson, D. Sethumadhavan, Marcus A. Tius

Organic Letters · 2005 · 42 citations · 5 references

DOI

Concepts

Abstract

[reaction: see text] Metalloenolates derived from alpha,beta-unsaturated alpha-diketones undergo cyclization to alpha-hydroxy cyclopentenones. This is apparently the first reported Nazarov reaction that takes place in the presence of base.

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